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Proakselerin
Struktur yang tersedia
PDB	Pencarian ortolog: PDBe RCSB
Daftar kode ID PDB
	3S9C, 1CZS, 1CZV, 3P6Z, 3P70
Pengidentifikasi
Alias	F5, FVL, PCCF, RPRGL1, THPH2, coagulation factor V
ID Eksternal	OMIM: 612309; MGI: 88382; HomoloGene: 104; GeneCards: F5; OMA:F5 - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 1 (manusia)
Akhir	169,586,588 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	right lobe of liver; ; Epithelium of choroid plexus; ; pancreatic ductal cell; ; plasenta; ; Saraf optik; ; Monosit; ; olfactory zone of nasal mucosa; ; darah; ; kantung empedu; ; Granulosit;
	Ekspresi tertinggi di
	Epithelium of choroid plexus; ; choroid plexus of fourth ventricle; ; left lobe of liver; ; Badan siliaris; ; Kelenjar Air Mata; ; darah; ; Selaput pelangi; ; Granulosit; ; tibiofemoral joint; ; parotid gland;
	Referensi data ekspresi selengkapnya
	; ;
	Data ekspresi referensi lebih lanjut
Ontologi gen
Fungsi molekuler	metal ion binding; Ikatan protein plasma; copper ion binding;
Komponen seluler	platelet alpha granule; Vesikel ekstraseluler; endoplasmic reticulum lumen; membran; membran sel; extracellular region; COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum-Golgi intermediate compartment membrane; platelet alpha granule lumen; badan Golgi; Retikulum endoplasma; Golgi membrane; extracellular space;
Proses biologis	Hemostasis; platelet degranulation; Koagulasi; blood circulation; endoplasmic reticulum to Golgi vesicle-mediated transport; COPII vesicle coating; response to vitamin K; modifikasi pascatranslasi;
	Sumber:Amigo / QuickGO
Ortologi
	2153
	14067
	ENSG00000198734
	ENSMUSG00000026579
	P12259
	O88783
	NM_000130
	NM_007976
	NP_000121
	NP_032002
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Proakselerin atau faktor V (bahasa Inggris: proaccelerin, labile factor, plasma accelerator globulin, plasma ac-globulin, accelerator globulin, proprothrombinase, prothrombin conversion accelerator I, Factor V, FV, activated protein C cofactor, factor V Leiden, PCCF, FVL, F5^[4]code: en is deprecated ) adalah metabolit berupa protein yang ditemukan dalam plasma darah yang merupakan prekursor dari akselerin.^[5] Proakselerin berguna demi mempercepat proses konversi protrombin menjadi trombin.^[6]

Proakselerin ditengarai juga bereaksi terhadap protein S.^[7]^[8]

Rujukan

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000198734 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ (Inggris) "coagulation factor V". Weizmann Institute of Science. Diakses tanggal 2010-04-28.
^ (Inggris) "proaccelerin". Mosby's Dental Dictionary; Elsevier, Inc. Diakses tanggal 2010-04-28.
^ (Inggris) "proaccelerin". McGraw-Hill Dictionary of Scientific & Technical Terms. Diakses tanggal 2010-04-28.
^ Heeb, M J (1999). "C-terminal residues 621-635 of protein S are essential for binding to factor Va". J. Biol. Chem. 274 (51). UNITED STATES: 36187–92. ISSN 0021-9258. PMID 10593904. ; ; ; ; Pemeliharaan CS1: Tahun (link)
^ Heeb, M J (1993). "Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C". J. Biol. Chem. 268 (4). UNITED STATES: 2872–7. ISSN 0021-9258. PMID 8428962. ; ; ; ; Pemeliharaan CS1: Tahun (link)

Bacaan lanjut

(Inggris) Mutation in blood coagulation factor V associated with resistance to activated protein C. Hemostasis and Thrombosis Research Center, University Hospital Leiden

Artikel bertopik biokimia ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000198734 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] (Inggris) "coagulation factor V". Weizmann Institute of Science. Diakses tanggal 2010-04-28.

[5] (Inggris) "proaccelerin". Mosby's Dental Dictionary; Elsevier, Inc. Diakses tanggal 2010-04-28.

[6] (Inggris) "proaccelerin". McGraw-Hill Dictionary of Scientific & Technical Terms. Diakses tanggal 2010-04-28.

[pmid10593904-7] Heeb, M J (1999). "C-terminal residues 621-635 of protein S are essential for binding to factor Va". J. Biol. Chem. 274 (51). UNITED STATES: 36187–92. ISSN 0021-9258. PMID 10593904. ; ; ; ; Pemeliharaan CS1: Tahun (link)

[pmid8428962-8] Heeb, M J (1993). "Binding of protein S to factor Va associated with inhibition of prothrombinase that is independent of activated protein C". J. Biol. Chem. 268 (4). UNITED STATES: 2872–7. ISSN 0021-9258. PMID 8428962. ; ; ; ; Pemeliharaan CS1: Tahun (link)

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