Ensiklopedia Dunia

Magnesium glisinat
Nama
	Nama IUPAC Magnesium diglisinat
	Nama IUPAC (sistematis) Magnesium bis(aminoasetat)
Penanda
Nomor CAS	14783-68-7 ;
Model 3D (JSmol)	Gambar interaktif;
ChemSpider	76358;
DrugBank	DB11189;
Nomor EC
PubChem CID	84645;
Nomor RTECS	{{{value}}}
UNII	IFN18A4Y6B ;
CompTox Dashboard (EPA)	DTXSID90163815 ;
	InChI InChI=1S/2C2H5NO2.Mg/c23-1-2(4)5;/h21,3H2,(H,4,5);/q;;+2/p-2 Key: AACACXATQSKRQG-UHFFFAOYSA-L;
	SMILES C(C(=O)[O-])N.C(C(=O)[O-])N.[Mg+2];
Sifat
Rumus kimia	C4H8MgN2O4
Massa molar	172,42 g·mol−1
	Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa).
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	Referensi

Magnesium glisinat, juga dikenal sebagai magnesium diglisinat atau magnesium bisglisinat, adalah garam magnesium dari glisina (satu atom magnesium dan dua molekul glisina), dan dijual sebagai suplemen makanan.^[1]^[2] Ia mengandung 14,1% unsur magnesium berdasarkan massa.

Magnesium glisinat juga sering "disangga" dengan magnesium oksida tetapi juga tersedia dalam bentuk magnesium glisinat murni tanpa penyangga.^[3]

Kegunaan

Magnesium glisinat telah dipelajari dengan penerapannya pada pasien dengan reseksi usus^[1] atau kram kaki akibat kehamilan.^[2] Penelitian ilmiah yang ada mengenai magnesium glisinat dalam aplikasi terapeutik lebih sedikit daripada bentuk garam magnesium yang lebih umum seperti magnesium klorida, oksida atau sitrat. Magnesium glisinat telah dipertimbangkan dalam konteks pengaruh potensial magnesium pada sistem yang terkait dengan perkembangan depresi.^[4]

Struktur kimia

Menurut kristalografi sinar-X, magnesium glisinat dapat hadir dalam beberapa bentuk, seringkali dengan anion lain.^[5]

Referensi

^ ^a ^b Schuette SA, Lashner BA, Janghorbani M (1994). "Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection". Journal of Parenteral and Enteral Nutrition. 18 (5): 430–5. doi:10.1177/0148607194018005430. PMID 7815675. Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.
^ ^a ^b Supakatisant C, Phupong V (2015). "Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial". Maternal & Child Nutrition. 11 (2): 139–45. doi:10.1111/j.1740-8709.2012.00440.x. PMC 6860204. PMID 22909270. Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.
^ "Magnesium Bisglycinate". 88Herbs. 20 November 2014.
^ Derom, Marie-Laure; Sayón-Orea, Carmen; Martínez-Ortega, José María; Martínez-González, Miguel A. (2013-09-01). "Magnesium and depression: a systematic review". Nutritional Neuroscience. 16 (5): 191–206. doi:10.1179/1476830512Y.0000000044. ISSN 1028-415X. PMID 23321048.
^ Clulow, Rebecca; Lightfoot, Philip (2018). "New sarcosine–metal halide complexes related to ferroelectric TSCC". CrystEngComm. 20 (28): 4012–4019. Bibcode:2018CEG....20.4012C. doi:10.1039/C8CE00719E.

[pmid7815675-1] Schuette SA, Lashner BA, Janghorbani M (1994). "Bioavailability of magnesium diglycinate vs magnesium oxide in patients with ileal resection". Journal of Parenteral and Enteral Nutrition. 18 (5): 430–5. doi:10.1177/0148607194018005430. PMID 7815675. Magnesium diglycinate may be a good alternative to commonly used magnesium supplements in patients with intestinal resection.

[pmid22909270-2] Supakatisant C, Phupong V (2015). "Oral magnesium for relief in pregnancy-induced leg cramps: a randomised controlled trial". Maternal & Child Nutrition. 11 (2): 139–45. doi:10.1111/j.1740-8709.2012.00440.x. PMC 6860204. PMID 22909270. Forty-one women were assigned to magnesium bisglycinate chelate (300 mg per day) and 39 women to placebo. Details of leg cramps were recorded before beginning the treatment and the fourth week of study.

[88Herbs-2014-3] "Magnesium Bisglycinate". 88Herbs. 20 November 2014.

[4] Derom, Marie-Laure; Sayón-Orea, Carmen; Martínez-Ortega, José María; Martínez-González, Miguel A. (2013-09-01). "Magnesium and depression: a systematic review". Nutritional Neuroscience. 16 (5): 191–206. doi:10.1179/1476830512Y.0000000044. ISSN 1028-415X. PMID 23321048.

[5] Clulow, Rebecca; Lightfoot, Philip (2018). "New sarcosine–metal halide complexes related to ferroelectric TSCC". CrystEngComm. 20 (28): 4012–4019. Bibcode:2018CEG....20.4012C. doi:10.1039/C8CE00719E.

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Ensiklopedia Dunia

Magnesium glisinat

Kegunaan

Struktur kimia

Referensi

Beranda

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