Ensiklopedia Dunia

KLF17
Pengidentifikasi
Alias	KLF17, ZNF393, Zfp393, Kruppel-like factor 17, Kruppel like factor 17, ZLF393
ID Eksternal	OMIM: 609602; MGI: 2181068; HomoloGene: 12621; GeneCards: KLF17; OMA:KLF17 - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 1 (manusia)
Akhir	44,135,140 pb
Lokasi gen (Tikus)
Kr.	Kromosom 4 (tikus)
Akhir	117,622,845 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	left testis; ; Testis; ; right testis; ; otot polos; ; Gonad; ; sperma; ; stromal cell of endometrium; ; right lung; ; left adrenal gland; ; right adrenal gland;
	Ekspresi tertinggi di
	Zigot; ; secondary oocyte; ; primary oocyte; ; spermatid; ; embrio; ; Uretra; ; male urethra; ; lumbar subsegment of spinal cord; ; morula; ; morula;
	Referensi data ekspresi selengkapnya
	n/a
Ontologi gen
Fungsi molekuler	DNA binding; Ikatan protein plasma; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific;
Komponen seluler	Inti sel;
Proses biologis	regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II; negative regulation of transcription by RNA polymerase II;
	Sumber:Amigo / QuickGO
Ortologi
	128209
	75753
	ENSG00000171872
	ENSMUSG00000048626
	Q5JT82
	Q8CFA7
	NM_173484
	NM_029416
	NP_775755
	NP_083692
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Krueppel-like factor 17 adalah protein yang pada manusia disandi oleh gen KLF17.^[5]^[6] KLF17 merupakan faktor transkripsi yang berperan sebagai penghambat langkah awal dalam metastasis kanker payudara.^[7]

Referensi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171872 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048626 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. Apr 2006. doi:10.1016/j.ygeno.2005.12.011. PMID 16460907.
^ "Entrez Gene: KLF17 Kruppel-like factor 17".
^ Huang, Qihong; Zhang, Lin; Coukos, George; Katsaros, Dionyssios; Showe, Louise C.; Klein-Szanto, Andres J.; Gimotty, Phyllis A.; Li, Anping; Gumireddy, Kiranmai (2009-11). "KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer". Nature Cell Biology (dalam bahasa Inggris). 11 (11): 1297–1304. doi:10.1038/ncb1974. ISSN 1476-4679. PMC 2784164. PMID 19801974. Pemeliharaan CS1: Format PMC (link)

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000171872 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048626 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16460907-5] "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. Apr 2006. doi:10.1016/j.ygeno.2005.12.011. PMID 16460907.

[entrez-6] "Entrez Gene: KLF17 Kruppel-like factor 17".

[7] Huang, Qihong; Zhang, Lin; Coukos, George; Katsaros, Dionyssios; Showe, Louise C.; Klein-Szanto, Andres J.; Gimotty, Phyllis A.; Li, Anping; Gumireddy, Kiranmai (2009-11). "KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer". Nature Cell Biology (dalam bahasa Inggris). 11 (11): 1297–1304. doi:10.1038/ncb1974. ISSN 1476-4679. PMC 2784164. PMID 19801974. Pemeliharaan CS1: Format PMC (link)

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KLF17

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