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Interleukin-5
Struktur yang tersedia
PDB	Pencarian ortolog: PDBe RCSB
Daftar kode ID PDB
	3VA2, 1HUL, 3QT2
Pengidentifikasi
Alias	IL5, EDF, IL-5, TRF, interleukin 5
ID Eksternal	OMIM: 147850; MGI: 96557; HomoloGene: 679; GeneCards: IL5; OMA:IL5 - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 5 (manusia)
Akhir	132,556,838 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	right testis; ; left testis; ; Tendon Achilles; ; right uterine tube; ; Corpus callosum; ; otot polos; ; Granulosit; ; right ovary; ; right coronary artery; ; Metanefros;
	Ekspresi tertinggi di
	embrio; ; perirhinal cortex; ; Kerongkongan; ; entorhinal cortex; ; CA3 field; ; Medula oblongata; ; timus; ; primary motor cortex;
	Referensi data ekspresi selengkapnya
	Data ekspresi referensi lebih lanjut
Ontologi gen
Fungsi molekuler	interleukin-5 receptor binding; Ikatan protein plasma; growth factor activity; protein tyrosine kinase activity; cytokine activity;
Komponen seluler	extracellular region; intracellular anatomical structure; extracellular space;
Proses biologis	positive regulation of DNA-binding transcription factor activity; positive regulation of podosome assembly; MAPK cascade; positive regulation of transcription, DNA-templated; respons imun; positive regulation of cell population proliferation; positive regulation of eosinophil differentiation; positive regulation of peptidyl-tyrosine phosphorylation; inflammatory response; positive regulation of receptor signaling pathway via JAK-STAT; peptidyl-tyrosine phosphorylation; positive regulation of B cell proliferation; regulation of signaling receptor activity; cytokine-mediated signaling pathway;
	Sumber:Amigo / QuickGO
Ortologi
	3567
	16191
	ENSG00000113525
	ENSMUSG00000036117
	P05113
	P04401
	NM_000879
	NM_010558
	NP_000870
	NP_034688
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Interleukin-5, IL-5 (bahasa Inggris: eosinophil colony-stimulating factor, EDF, TRFcode: en is deprecated ) adalah sitokina sekresi sel T_H^[4] yang berperan dalam perkembangan dan diferensiasi sel B dan eosinofil.^[5]

Peningkatan rasio IL-5 dilaporkan terkait dengan asma dan sindrom hipereosinofilik,^[5] seperti eosinofilia.^[6] Tingginya rasio IL-5 juga ditemukan pada penderita penyakit Graves dan tiroiditis Hashimoto.^[7]

Referensi

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113525 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ (Inggris) "Naive helper T cells from BCG-vaccinated volunteers produce IFN-gamma and IL-5 to mycobacterial antigen-pulsed dendritic cells". Department of Immunology and Infectious Biology, University of Lodz; Kowalewicz-Kulbat M, Kaźmierczak D, Donevski S, Biet F, Pestel J, Rudnicka W. Diakses tanggal 2010-06-08.
^ ^a ^b (Inggris) "1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-06-08.
^ (Inggris) "TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas". Department of Pathology, CHU of Liège, University of Liège; Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L. Diakses tanggal 2010-06-08.
^ (Inggris) "The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease". Defence Bio-engineering and Electromedical Laboratory; Gopalakrishnan S, Sen S, Adhikari JS, Chugh PK, Sekhri T, Rajan S. Diakses tanggal 2010-06-08.

Artikel bertopik biokimia ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113525 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] (Inggris) "Naive helper T cells from BCG-vaccinated volunteers produce IFN-gamma and IL-5 to mycobacterial antigen-pulsed dendritic cells". Department of Immunology and Infectious Biology, University of Lodz; Kowalewicz-Kulbat M, Kaźmierczak D, Donevski S, Biet F, Pestel J, Rudnicka W. Diakses tanggal 2010-06-08.

[entrez_3567-5] (Inggris) "1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-06-08.

[6] (Inggris) "TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas". Department of Pathology, CHU of Liège, University of Liège; Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L. Diakses tanggal 2010-06-08.

[7] (Inggris) "The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease". Defence Bio-engineering and Electromedical Laboratory; Gopalakrishnan S, Sen S, Adhikari JS, Chugh PK, Sekhri T, Rajan S. Diakses tanggal 2010-06-08.

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Basis data pengawasan otoritas
Nasional	Amerika Serikat Israel
Lain-lain	Yale LUX

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Interleukin-5

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