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EIF2AK4
Struktur yang tersedia
PDB	Pencarian ortolog: PDBe RCSB
Daftar kode ID PDB
	1UKX, 4OTN
Pengidentifikasi
Alias	EIF2AK4, GCN2, PVOD2, eukaryotic translation initiation factor 2 alpha kinase 4
ID Eksternal	OMIM: 609280; MGI: 1353427; HomoloGene: 40891; GeneCards: EIF2AK4; OMA:EIF2AK4 - orthologs
Lokasi gen (Manusia)
Kr.	Kromosom 15 (manusia)
Akhir	40,035,591 pb
Pola ekspresi RNA
	Ekspresi tertinggi di
	Adenohipofisis; ; bone marrow cell; ; stromal cell of endometrium; ; Membran sinovial; ; Tulang kering; ; Tendon Achilles; ; Brodmann area 9; ; nucleus accumbens; ; left uterine tube; ; caudate nucleus;
	Ekspresi tertinggi di
	medullary collecting duct; ; secondary oocyte; ; primary oocyte; ; Zigot; ; Sacculus dan utriculus; ; otic placode; ; Paneth cell; ; external carotid artery; ; epithelium of lens; ; internal carotid artery;
	Referensi data ekspresi selengkapnya
	n/a
Ontologi gen
Fungsi molekuler	transferase activity; nucleotide binding; protein kinase activity; tRNA binding; kinase activity; protein serine/threonine kinase activity; RNA binding; ATP binding; eukaryotic translation initiation factor 2alpha kinase activity;
Komponen seluler	sitoplasma; polysome; cytosolic ribosome;
Proses biologis	positive regulation of translational initiation in response to starvation; adaptive immune response; negative regulation of neuron differentiation; positive regulation of long-term synaptic potentiation; positive regulation of adaptive immune response; negative regulation of translational initiation in response to stress; negative regulation of translational initiation; Fosforilasi; immune system process; cellular response to UV; cellular response to amino acid starvation; negative regulation of CREB transcription factor activity; regulation of feeding behavior; belajar; perkembangan sistem saraf; viral translation; neuron projection extension; protein phosphorylation; cellular response to cold; long-term memory; defense response to virus; cellular response to leucine starvation; eiF2alpha phosphorylation in response to endoplasmic reticulum stress; induction by virus of host autophagy; protein autophosphorylation; Siklus sel; negative regulation by host of viral genome replication; viral process; regulation of translation; regulation of translational initiation; positive regulation of defense response to virus by host; T cell activation involved in immune response; DNA damage checkpoint signaling; regulation of translational initiation by eIF2 alpha phosphorylation;
	Sumber:Amigo / QuickGO
Ortologi
	440275
	27103
	ENSG00000128829
	ENSMUSG00000005102
	Q9P2K8
	Q9QZ05
	NM_001013703
	NM_001177806; NM_013719; NM_001355383
	NP_001013725
	NP_001171277; NP_038747; NP_001342312
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus