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Betametason valerat
Data klinis
Nama dagang	Benczema, Benoson, dll
Nama lain	Betametason 17-valerat
AHFS/Drugs.com	monograph
Kelas obat	Corticosteroid; glucocorticoid
Pengenal
	Nama IUPAC (11β,16β)-9-Fluoro-11,21-dihidroksi-16-metil-3,20-dioksopregna-1,4-dien-17-il valerat;
Nomor CAS	2152-44-5;
PubChem CID	16533;
ChemSpider	15673;
UNII	9IFA5XM7R2;
ChEBI	CHEBI:31277 ;
ChEMBL	ChEMBL1497 ;
CompTox Dashboard (EPA)	DTXSID7022673 ;
ECHA InfoCard	100.016.764
Data sifat kimia dan fisik
Rumus	C27H37FO6
Massa molar	476,59 g·mol−1
Model 3D (JSmol)	Gambar interaktif;
	SMILES CCCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO;
	InChI InChI=1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19-,20-,21-,24-,25-,26-,27-/m0/s1 ; Key:SNHRLVCMMWUAJD-SUYDQAKGSA-N ;

Betametason valerat adalah ester glukokortikoid sintetis. Ini adalah ester 17-valerat dari betametason.^[1]^[2] Betametason valerat sering digunakan untuk mengobati eksim ringan dengan kemanjuran yang baik dan insiden efek samping yang disebabkan steroid yang lebih rendah karena potensinya yang lebih rendah dibandingkan dengan glukokortikoid lainnya. Betametason-17-valerat tersedia dalam bentuk krim, salep, losion, dan sediaan busa untuk penggunaan topikal.^[3]^[4]^[5]

Referensi

^ Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.
^ "Betamethasole valerate". PubChem. U.S. National Library of Medicine.
^ Raveendran R (November 2019). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America. 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. PMID 31563186. S2CID 202816063.
^ Payne J, Habet KA, Pona A, Feldman SR (August 2019). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. PMID 31424707.
^ Duweb GA, Abuzariba O, Rahim M, al-Taweel M, Abdulla SA (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. PMID 11314240.

[1] Ly S, Amici JM (2018). "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context. 7: 212539. doi:10.7573/dic.212539. PMC 6104053. PMID 30151017.

[2] "Betamethasole valerate". PubChem. U.S. National Library of Medicine.

[:0-3] Raveendran R (November 2019). "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America. 39 (4): 521–533. doi:10.1016/j.iac.2019.07.006. PMID 31563186. S2CID 202816063.

[4] Payne J, Habet KA, Pona A, Feldman SR (August 2019). "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology. 18 (8): 756–770. PMID 31424707.

[5] Duweb GA, Abuzariba O, Rahim M, al-Taweel M, Abdulla SA (2000). "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research. 20 (3–4): 65–68. PMID 11314240.

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Betametason valerat

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